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THE PHILOSOPHICAL THINKING AND THE AGING

...la, an individuality to a generality. The generality can be unconditioned or conditioned. But, ho can be modeled, in a similar ay, the theories from the Medvedevs rational clasification I consider that, most theories clasified by Medvedev are causaly explanatory. A set of phenotypes causes agings phenotypes. For instance, ROS causes lesions, lesions also mean aging, aging is caused also by ROS. Or, myelins deterioration or thiness causes the decrease of the protective poer of the neuron. That decrease causes vulnerability to certain physical stressors. That is hy, the neuronal death is conditioned also by the loss or deterioration of myelin. Important age-related neuronal losses causes cognitive aging. Telomeric changes causes replicative senescence Hayflick, 1983.That is hy, it seems that, e can formalize conjunctively Medvedevs clasification in the foloing ay c1c2 ...cX causes e1e2e3...eXAGING. here ci are causes and ei are effects. Hoever, c1, c2, ..., cX can contain causes from different levels. Some causes do not determ directly behavioral aging, but there exist causal chains that determ only finaly behavioral aging. That is, there are indirect interactions beteen different levels cognitive and non-cognitive, tissular and intracellular etc., that is, certain bidirectionalities. Because all of this, the first premise of an explanatory reasoning cannot have, in our case, a simple C causes E form. Ho simple as all in antiquityP1 People are mortal.P2 Socrates is man.C Socrates is mortal.orP1 People undergoes aging, naturaly.P2 Socrates is man.Condition1 are excluded the anti-aging actions.Condition2 is excluded the death by accident or incurable diseases.Conclusion Socrates undergoes aging.P1 xixIHAxs.P2 Socrates belongs to H.C Aging Socrates.o r , xixIHAxsIHsAS.These reasonings extend a general intensional element to an individual that belong to a set-extension, but, it seems that, are non-explanatory. The characteristic or process that e have to explain is the characteristic of an object, a bio-object. Aging is not an absolute entity. Hoever, e do not ant to explain the aging of an individual man, but the human aging in general. The dificulty consists not in the extentension of a property to an individual, it seems. The actual scientific explanation of aging does not fit naturaly Hempels model. e need a fundamental abstract understanding of aging. Aging implies quantitative and qualitative cellular changes. And also changes of the intercellular environment. Many aging-related quantitative cellular losses are caused by apoptosis conditioned by qualitative factors. The aging of the biohole is not reducible to the loss of its fundamental redundat bioparts.Medvedevs rational clasification of the scientific theories of aging represents a multiplicity diversified in about six clases1. The theories of genetical programs.2. The theories of the first lesions.3. The theories based on the analysis of the manifestations of senescence at molecular, cellular, and organic levels.4. The evolutionary theories.5. The theories of aging of some particular tissues.6. The unificatory theories.Considering this theoretical clases and trying to adapt them to the standard model of scientific explanation, I arrived at the foloing resultsA. The causes and conditions of aging are present at different levels of the organisation of matter f.i., atomic, molecular, tissular-cognitive some conditions are even metaphysical the absence of some perfect preventive and reparative mechanisms. That is hy, a complete explanation cannot be causal and reductionist.B. There can be no a scientific complete biouniversal explanation of aging, in the sense that, the bioarchitectural differences bring ne causes and conditions of aging hich cannot be refounded in the explanation of other objects aging.C. The standard model DN of scientific explanation implies the deduction or subsumation of an individual or particular case under a general case the standard models general is nomologic. This makes the first difficulty in the attempt of adaptation of the scientific explanation of aging, a complex reality, ith the Hempelian nomological model of explanation. Hoever, the problem of logical ordering of the explanation of aging become solvable, discovering the possibility of a regress to a more fundamental logicity. Thus, e can discover that beteen hat explanates and hat is explanated there have to be an implicative relation. hat mens that, hat explanates have to constitute a suficient condition to determ a necessary consequence-conclusion. Therefore, the theoretical corpus ould have to form a suficient condition, for the derivation of an individual case, at least together ith certain conditions.D. The discovery that, the disjunction or the conjunction of the theories of aging does not form a suficient condition for the derivation of conclusion about the aging of a concrete individual, until there is no an universaly accepted demonstration about the impossibility of eradication of aging.E. the discovery of some fundamental auxiliary conditions hich can increase effectively the logical poer of the explanatory reasoning i the exclusion of the anti-aging actions thus, it is devisioused hat is no the too hard problem of the possibility of eradication of aging.ii the exclusion of accidental death.F. the understanding that, supposing the truth of all theories, their causes are suficient to effectuate aging, but if the list of causes is incomplete, than, on the one hand, the explanation substantiated by it ill cannot predict ith precision the mean trajectory of the process of aging, and, on the other hand, the strategical project designed to substantiate the actions for the eradication of aging founded on that list ill be non-completely effective.2. THE MIND AND THE AGINGA superior part of the cognitive aging is caused by the loss of synchronization of the activities of some cognitive neuronal netorks. This loss is caused by the decrease of the speed of transmission of action potentials. The decrease of speed is caused by a neuronal qualitative change, the alteration of myielin Bartzokis, 2003, not by a by a cellular loss, hich ould mean a negative quantitative numerical cellular change. The speed of interneuronal communication depends on neuroqualitative characteristics. The neurons main functional characteristics depend on the neurons hole structure aleration and on the alteration of the interneuronal environment.Some alterations are clearly directly destructive, as those caused by ROS action, some aging-related alterations, it seems that, are not de-structurative, as are the cross-links. The relations beteen the neuronal cells are comunicative and are important for the causation and conditionation of the higher order cognitive capacities. That is, they also are important in the explanation of the CNS aging. Considering the senses of the main causes of aging presented actualy in the science of aging, I consider that aging impl...
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